The code block below illustrates how one might use # and // as comments in your logic and calculations.
# Text can be put here to explain what the logic/calculation does and why.
if ([field1] = '1' and [field2] > 7,
// This comment can explain what the next line does.
[score] * [factor],
// Return '0' if the condition is False.
0
)
Working …
0% means
50% means
100% means
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Thank you for your interest in this research study. The purpose of this study is to learn more about metabolic responses to aerobic exercise at different times of the day (morning or evening) under fasting versus fed conditions. We want to understand if exercise timing and fed vs fasting status prior to exercise has an effect on energy metabolism. If you join this research study, you will participate in 5 consecutive days of 1) morning, fasted exercise (Fasted-AM), 2) morning, fed exercise (Fed-AM), 3) evening, fasted exercise (Fasted-PM), and 4) evening, fed exercise (Fed-PM). After each exercise condition you will wait ~2-4 weeks before beginning the next condition of exercise. Your total study exercise participation will last up to 5-8 months.
If you participate you will be assigned to a randomized sequence of Fasted-AM exercise, Fed-AM exercise, Fasted-PM exercise, Fed-PM exercise. We will provide you with access to the Anschutz Health and Wellness Center (AHWC) Fitness Center for all exercise sessions. For each of the conditions, you will perform supervised, moderate intensity, aerobic exercise on 5 consecutive days for 45 minutes each day. All exercise will be done on a treadmill and all exercise sessions will be tracked and verified using a heart rate monitor and phone application. During each exercise condition, you will be required to exercise at the AHWC exercise facility for four days in a row. The fifth day of exercise will be completed as a submaximal exercise metabolism test. Some participants will also be asked to complete an optional 24-hour stay in a special inpatient hospital room on the Anschutz Medical Campus called a Whole Room Indirect Calorimeter (WRIC) on day 6 of each condition.
During days 3 and 4 of each of the exercise conditions, the study will provide you with meals. During this time, you will be asked to consume only the meals provided and nothing else but water. For the Fed-AM, Fed-PM, and Fasted-AM conditions, three meals will be provided (breakfast, lunch, and dinner) each comprising 33% of the energy content for the day. For the Fasted-PM condition, the study will provide you with breakfast and dinner meals that equal about half of the normal energy content for the day. You will be given the exact amount of calories you are burning (i.e., not overfed and not underfed). On day 5 during the Fed-PM condition you will receive breakfast, lunch, and dinner. During the Fed-AM and Fasted-PM conditions you will receive breakfast on day 5. During the Fasted-AM condition you will not receive any meals on day 5.The 4 different study exercise conditions are outlined below.
Completed in a Randomized Order:
Fasted-AM - you will exercise within 4 hours of waking up, after an overnight fast on 4 consecutive days leading up to the day 5 exercise metabolism assessment. You will be asked to consume study provided meals at ~8:00AM, ~1:00PM, and ~7:00PM.
Fed-AM - you will exercise within 4 hours of waking up, approximately 1h after consuming breakfast on 4 consecutive days leading up to the day 5 exercise metabolism assessment. On day 5, you will receive breakfast. You will be asked to consume study provided meals at ~7:00AM, ~12:00PM, and ~6:00PM.
Fasted-PM - you will exercise between 8-12 hours after waking up, following a ~10h fast on 4 consecutive days leading up to the day 5 exercise metabolism assessment. On day 5, you will receive breakfast. You will be asked to consume study provided meals at ~7:00AM and ~6:00PM.
Fed-PM - you will exercise between 8-12 hours after waking up, approximately 1h after consuming dinner on 4 consecutive days leading up to the day 5 exercise metabolism assessment. On day 5, you will receive breakfast, lunch, and dinner. You will be asked to consume study provided meals at ~7:00AM, ~12:00PM, and ~6:00PM.
During each of the exercise conditions, you will be asked to maintain normal sleep habits and sleep duration.
Prior to the study you will be asked to complete a screening visit to confirm your eligibility for the study. This visit will last approximately 1 hour. You may be asked to fast before you come in for your first study visit because you may do a fasted blood draw. This means you cannot eat anything, or drink anything except for water for 12 hours before your appointment. When you fast, you may feel lightheaded, dizzy, and/or weak. During the study you will undergo assessments of your body weight, body composition, laboratory values, exercise capacity, physical activity, sleep, dietary patterns, and other diet and exercise behaviors.
Before you come in to learn more about the study, it would be helpful to see if you are likely to qualify to be in the study. In order to do this, we would like to ask you some eligibility questions, which will include questions about your health history, including questions about your mental health and drug and alcohol use. It should take about 15-20 minutes to go through these questions. Some of the questions may make you uncomfortable; you do not have to answer any question that you would not like to answer, but without answers to these questions, we will not be able to determine if you are eligible to participate in the study. We will collect your name and contact information, but we will use an identification code (rather than your name) on the form we use to record your answers. If you do not enroll in this study, we will keep the information collected during this pre-screening secure. We are also required to give you the number of COMIRB, the Ethics Board that oversees our research: it is (303) 724-1055, in case you have any questions or concerns for them.
If you have any questions about the screening questions, please call contact the study team at justin.lorentzen@cuanschutz.edu.
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